SCOPe 2.08: Domain d7avva_: 7avv A:

Lineage for d7avva_ (7avv A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.117: Ras GEF [48365] (1 superfamily)
   multihelical

4. Superfamily a.117.1: Ras GEF [48366] (1 family)

5. Family a.117.1.1: Ras GEF [48367] (2 proteins)

6. Protein Son of sevenless protein homolog 1 (sos-1) [48368] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48369] (60 PDB entries)
   Uniprot Q07889 189-1046

8. Domain d7avva_: 7avv A: [401666]
   automated match to d1nvus_
   complexed with imd, s2w

Details for d7avva_

PDB Entry: 7avv, 2.12 Å

PDB Description: crystal structure of sos1 in complex with compound 9

PDB Compounds: (A:) Son of sevenless homolog 1

SCOPe Domain Sequences for d7avva_:

Sequence, based on SEQRES records:

>d7avva_ a.117.1.1 (A:) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
eqmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnfv
rtflttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqp
vqlrvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiar
dngpghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpsel
vgsvwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvfqe
lnnfngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinp
pcvpffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrve
sdikrffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrp

Sequence, based on observed residues (ATOM records):

>d7avva_ a.117.1.1 (A:) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
eqmrlpsadvyrfaepdseeniifegipiikagtviklierltyhmyadpnfvrtfltty
rsfckpqellsliierfeipepepteaplsaelkrfrkeyiqpvqlrvlnvcrhwvehhf
ydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiafqsspptvewhisrpghi
etfdlltlhpieiarqltllesdlyravqpselvgsveinspnllkmirhttnltlwfek
civetenleervavvsriieilqvfqelnnfngvlevvsamnsspvyrldhtfeqipsrq
kkileeahelsedhykkylaklrsinppcvpffgiyltnilkteegnpevlkrhgkelin
fskrrkvaeitgeiqqyqnqpyclrvesdikrffenlnpmgnsmekeftdylfnksleie
prnpkplprfpkkysyplkspgvrp

Timeline for d7avva_:

• d7avva_ first appeared in SCOPe 2.07