SCOP 1.67: Domain d5grt_3: 5grt 364-478

Lineage for d5grt_3 (5grt 364-478)

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.87: CO dehydrogenase flavoprotein C-domain-like [55423] (2 superfamilies)
   core: beta(3,4)-alpha(3); alpha+beta sandwich

4. Superfamily d.87.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55424] (1 family)
   both first two domains are of same beta/beta/alpha fold

5. Family d.87.1.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55425] (10 proteins)

6. Protein Glutathione reductase [55426] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55427] (17 PDB entries)

8. Domain d5grt_3: 5grt 364-478 [40164]
   Other proteins in same PDB: d5grt_1, d5grt_2
   complexed with fad, ts4; mutant

Details for d5grt_3

PDB Entry: 5grt, 2.4 Å

PDB Description: human glutathione reductase a34e, r37w mutant, glutathionylspermidine complex

SCOP Domain Sequences for d5grt_3:

Sequence; same for both SEQRES and ATOM records:

>d5grt_3 d.87.1.1 (364-478) Glutathione reductase {Human (Homo sapiens)}
ynniptvvfshppigtvgltedeaihkygienvktystsftpmyhavtkrktkcvmkmvc
ankeekvvgihmqglgcdemlqgfavavkmgatkadfdntvaihptsseelvtlr

Timeline for d5grt_3:

• d5grt_3 first appeared (with stable ids) in SCOP 1.55
  
• d5grt_3 appears in SCOP 1.65
  
• d5grt_3 appears in SCOP 1.69
  
• d5grt_3 appears in the current release, SCOPe 2.08, called d5grta3