SCOP 1.75: Domain d4gr1a3: 4gr1 A:364-478

Lineage for d4gr1a3 (4gr1 A:364-478)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.87: CO dehydrogenase flavoprotein C-domain-like [55423] (2 superfamilies)
   core: beta(3,4)-alpha(3); alpha+beta sandwich

4. Superfamily d.87.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55424] (1 family)
   both first two domains are of same beta/beta/alpha fold

5. Family d.87.1.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55425] (11 proteins)

6. Protein Glutathione reductase [55426] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55427] (17 PDB entries)

8. Domain d4gr1a3: 4gr1 A:364-478 [40162]
   Other proteins in same PDB: d4gr1a1, d4gr1a2
   complexed with fad, po4, rgs

Details for d4gr1a3

PDB Entry: 4gr1, 2.4 Å

PDB Description: the binding of the retro-analogue of glutathione disulfide to glutathione reductase

PDB Compounds: (A:) glutathione reductase

SCOP Domain Sequences for d4gr1a3:

Sequence; same for both SEQRES and ATOM records:

>d4gr1a3 d.87.1.1 (A:364-478) Glutathione reductase {Human (Homo sapiens) [TaxId: 9606]}
ynniptvvfshppigtvgltedeaihkygienvktystsftpmyhavtkrktkcvmkmvc
ankeekvvgihmqglgcdemlqgfavavkmgatkadfdntvaihptsseelvtlr

Timeline for d4gr1a3:

• d4gr1a3 first appeared (with stable ids) in SCOP 1.55, called d4gr1_3
  
• d4gr1a3 appears in SCOP 1.73
  
• d4gr1a3 appears in SCOPe 2.01
  
• d4gr1a3 appears in the current release, SCOPe 2.08