SCOP 1.69: Domain d1grf_3: 1grf 364-478

Lineage for d1grf_3 (1grf 364-478)

1. Root: SCOP 1.69

2. Class d: Alpha and beta proteins (a+b) [53931] (279 folds)

3. Fold d.87: CO dehydrogenase flavoprotein C-domain-like [55423] (2 superfamilies)
   core: beta(3,4)-alpha(3); alpha+beta sandwich

4. Superfamily d.87.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55424] (1 family)
   both first two domains are of same beta/beta/alpha fold

5. Family d.87.1.1: FAD/NAD-linked reductases, dimerisation (C-terminal) domain [55425] (10 proteins)

6. Protein Glutathione reductase [55426] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55427] (17 PDB entries)

8. Domain d1grf_3: 1grf 364-478 [40160]
   Other proteins in same PDB: d1grf_1, d1grf_2

Details for d1grf_3

PDB Entry: 1grf, 2 Å

PDB Description: substrate binding and catalysis by glutathione reductase as derived from refined enzyme: substrate crystal structures at 2 angstroms resolution

SCOP Domain Sequences for d1grf_3:

Sequence; same for both SEQRES and ATOM records:

>d1grf_3 d.87.1.1 (364-478) Glutathione reductase {Human (Homo sapiens)}
ynniptvvfshppigtvgltedeaihkygienvktystsftpmyhavtkrktkcvmkmvc
ankeekvvgihmqglgcdemlqgfavavkmgatkadfdntvaihptsseelvtlr

Timeline for d1grf_3:

• d1grf_3 first appeared (with stable ids) in SCOP 1.55
  
• d1grf_3 appears in SCOP 1.67
  
• d1grf_3 appears in SCOP 1.71
  
• d1grf_3 appears in the current release, SCOPe 2.08, called d1grfa3