SCOPe 2.08: Domain d6ls4b2: 6ls4 B:244-429

Lineage for d6ls4b2 (6ls4 B:244-429)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.79: Bacillus chorismate mutase-like [55297] (9 superfamilies)
   core: beta-alpha-beta-alpha-beta(2); mixed beta-sheet: order: 1423, strand 4 is antiparallel to the rest

4. Superfamily d.79.2: Tubulin C-terminal domain-like [55307] (2 families)

5. Family d.79.2.1: Tubulin, C-terminal domain [55308] (4 proteins)

6. Protein automated matches [227071] (7 species)
   not a true protein

7. Species Pig (Sus scrofa) [TaxId:9823] [278816] (66 PDB entries)

8. Domain d6ls4b2: 6ls4 B:244-429 [399814]
   Other proteins in same PDB: d6ls4a1, d6ls4b1, d6ls4c1, d6ls4d1, d6ls4e1, d6ls4e2
   automated match to d3rycd2
   complexed with gdp, gol, gtp, mes, mg, s40

Details for d6ls4b2

PDB Entry: 6ls4, 2.4 Å

PDB Description: a novel anti-tumor agent s-40 in complex with tubulin

PDB Compounds: (B:) Tubulin beta chain

SCOPe Domain Sequences for d6ls4b2:

Sequence, based on SEQRES records:

>d6ls4b2 d.79.2.1 (B:244-429) automated matches {Pig (Sus scrofa) [TaxId: 9823]}
gqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdsknmmaac
dprhgryltvaaifrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprglkm
satfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvseyq
qyqdat

Sequence, based on observed residues (ATOM records):

>d6ls4b2 d.79.2.1 (B:244-429) automated matches {Pig (Sus scrofa) [TaxId: 9823]}
gqlnadlrklavnmvpfprlhffmpgfapltsraltvpeltqqmfdsknmmaacdprhgr
yltvaaifrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprglkmsatfig
nstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvseyqqyqdat

Timeline for d6ls4b2:

• d6ls4b2 first appeared in SCOPe 2.07