Lineage for d7l0ne_ (7l0n E:)

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2570195Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. 2570196Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families) (S)
  5. 2570477Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
    combines M2, M3 and M32 families of metalloproteases
    the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain
  6. 2570478Protein Angiotensin converting enzyme 2, ACE2 [103125] (2 species)
  7. 2570481Species Human (Homo sapiens) [TaxId:9606] [103126] (20 PDB entries)
  8. 2570485Domain d7l0ne_: 7l0n E: [399565]
    Other proteins in same PDB: d7l0nb1, d7l0nb2, d7l0nd1, d7l0nd2, d7l0nl1, d7l0nl2, d7l0nn1, d7l0nn2, d7l0nr_, d7l0ns_
    automated match to d3scia_
    complexed with cl, na, nag, pg4, pg5, pge, so4, zn

Details for d7l0ne_

PDB Entry: 7l0n (more details), 2.78 Å

PDB Description: circulating sars-cov-2 spike n439k variants maintain fitness while evading antibody-mediated immunity
PDB Compounds: (E:) Angiotensin-converting enzyme 2

SCOPe Domain Sequences for d7l0ne_:

Sequence, based on SEQRES records: (download)

>d7l0ne_ d.92.1.5 (E:) Angiotensin converting enzyme 2, ACE2 {Human (Homo sapiens) [TaxId: 9606]}
stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspya

Sequence, based on observed residues (ATOM records): (download)

>d7l0ne_ d.92.1.5 (E:) Angiotensin converting enzyme 2, ACE2 {Human (Homo sapiens) [TaxId: 9606]}
stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgpglneima
nsldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvd
gydysrgqliedvehtfeeikplyehlhayvraklmnaypsyispclpahllgdmwgrfw
tnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltd
pgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllrng
anegfheavgeimslsaatpkhlksigllspdfqedneteinfllkqaltivgtlpftym
lekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycdpaslfhvsndysfiry
ytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvg
aknmnvrpllnyfeplftwlkdqnknsfvgwstdwspya

SCOPe Domain Coordinates for d7l0ne_:

Click to download the PDB-style file with coordinates for d7l0ne_.
(The format of our PDB-style files is described here.)

Timeline for d7l0ne_: