SCOPe 2.05: Domain d3gpdr2: 3gpd R:151-314

Lineage for d3gpdr2 (3gpd R:151-314)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.81: FwdE/GAPDH domain-like [55346] (4 superfamilies)
   core: alpha-beta-alpha-beta(3); mixed sheet: 2134, strand 2 is parallel to strand 1

4. Superfamily d.81.1: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain [55347] (5 families)
   N-terminal domain is the classic Rossmann-fold

5. Family d.81.1.1: GAPDH-like [55348] (6 proteins)
   has many additional secondary structures

6. Protein Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [55349] (19 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55360] (1 PDB entry)

8. Domain d3gpdr2: 3gpd R:151-314 [39943]
   Other proteins in same PDB: d3gpdg1, d3gpdr1
   complexed with nad, so4

Details for d3gpdr2

PDB Entry: 3gpd, 3.5 Å

PDB Description: twinning in crystals of human skeletal muscle d-glyceraldehyde-3- phosphate dehydrogenase

PDB Compounds: (R:) d-glyceraldehyde-3-phosphate dehydrogenase

SCOPe Domain Sequences for d3gpdr2:

Sequence; same for both SEQRES and ATOM records:

>d3gpdr2 d.81.1.1 (R:151-314) Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) {Human (Homo sapiens) [TaxId: 9606]}
cttnclaplakvihdhfgiveglmttvhaitatqktvdspsgklwrggrgaaqnlipast
gaakavgkvipeldgkltgmafrvptanvsvldltcrlekpakyddikkvvkeasegplk
gilgytedevvsddfngsnhssifdagagielndtfvklvswyd

Timeline for d3gpdr2:

• d3gpdr2 first appeared (with stable ids) in SCOP 1.55
  
• d3gpdr2 appears in SCOPe 2.04
  
• d3gpdr2 appears in SCOPe 2.06
  
• d3gpdr2 appears in the current release, SCOPe 2.08