Lineage for d6v8dc_ (6v8d C:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2502820Fold c.67: PLP-dependent transferase-like [53382] (3 superfamilies)
    main domain: 3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3245671; strand 7 is antiparallel to the rest
  4. 2502821Superfamily c.67.1: PLP-dependent transferases [53383] (10 families) (S)
  5. 2503664Family c.67.1.4: GABA-aminotransferase-like [53417] (17 proteins)
    formerly omega-Aminoacid:pyruvate aminotransferase-like
  6. 2503822Protein Ornithine aminotransferase [53422] (3 species)
  7. 2503823Species Human (Homo sapiens) [TaxId:9606] [53423] (11 PDB entries)
  8. 2503853Domain d6v8dc_: 6v8d C: [397883]
    automated match to d2byja1
    complexed with o78, plp

Details for d6v8dc_

PDB Entry: 6v8d (more details), 2.25 Å

PDB Description: design, synthesis, and mechanism of fluorine-substituted cyclohexene analogues of gama-aminobutyric acid (gaba) as selective ornithine aminotransferase inactivators
PDB Compounds: (C:) Ornithine aminotransferase, mitochondrial

SCOPe Domain Sequences for d6v8dc_:

Sequence; same for both SEQRES and ATOM records: (download)

>d6v8dc_ c.67.1.4 (C:) Ornithine aminotransferase {Human (Homo sapiens) [TaxId: 9606]}
ptsddifereykygahnyhplpvalergkgiylwdvegrkyfdflssysavnqghchpki
vnalksqvdkltltsrafynnvlgeyeeyitklfnyhkvlpmntgveagetacklarkwg
ytvkgiqkykakivfaagnfwgrtlsaissstdptsydgfgpfmpgfdiipyndlpaler
alqdpnvaafmvepiqgeagvvvpdpgylmgvrelctrhqvlfiadeiqtglartgrwla
vdyenvrpdivllgkalsgglypvsavlcdddimltikpgehgstyggnplgcrvaiaal
evleeenlaenadklgiilrnelmklpsdvvtavrgkgllnaiviketkdwdawkvclrl
rdngllakpthgdiirfapplvikedelresieiinktilsf

SCOPe Domain Coordinates for d6v8dc_:

Click to download the PDB-style file with coordinates for d6v8dc_.
(The format of our PDB-style files is described here.)

Timeline for d6v8dc_: