Lineage for d6vcjb_ (6vcj B:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2510888Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2510889Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2510890Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. 2511215Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)
  7. 2511263Species Human (Homo sapiens) [TaxId:9606] [53607] (79 PDB entries)
  8. 2511342Domain d6vcjb_: 6vcj B: [395916]
    automated match to d1kmva_
    complexed with fol, lg3, nap, npx

Details for d6vcjb_

PDB Entry: 6vcj (more details), 2.34 Å

PDB Description: crystal structure of hsdhfr in complex with nadp+, dap, and r-naproxen
PDB Compounds: (B:) dihydrofolate reductase

SCOPe Domain Sequences for d6vcjb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d6vcjb_ c.71.1.1 (B:) Dihydrofolate reductases, eukaryotic type {Human (Homo sapiens) [TaxId: 9606]}
gslncivavsqnmgigkngdlpwpplrnefryfqrmtttssvegkqnlvimgkktwfsip
eknrplkgrinlvlsrelkeppqgahflsrslddalklteqpelankvdmvwivggssvy
keamnhpghlklfvtrimqdfesdtffpeidlekykllpeypgvlsdvqeekgikykfev
yekn

SCOPe Domain Coordinates for d6vcjb_:

Click to download the PDB-style file with coordinates for d6vcjb_.
(The format of our PDB-style files is described here.)

Timeline for d6vcjb_: