Lineage for d6t9ta_ (6t9t A:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2794584Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2794585Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2794859Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)
  6. 2795691Protein Matriptase MTSP1 [69284] (1 species)
  7. 2795692Species Human (Homo sapiens) [TaxId:9606] [69285] (21 PDB entries)
  8. 2795697Domain d6t9ta_: 6t9t A: [395691]
    automated match to d3ncla_
    complexed with cl, mxh

Details for d6t9ta_

PDB Entry: 6t9t (more details), 1.69 Å

PDB Description: matriptase in complex with the synthetic inhibitor (s)-3-(3-(4-(3- (tert-butyl)ureido)piperidin-1-yl)-2-((3'-fluoro-4'-(hydroxymethyl)- [1,1'-biphenyl])-3-sulfonamido)-3-oxopropyl)benzimidamide (mi-1904)
PDB Compounds: (A:) Suppressor of tumorigenicity 14 protein

SCOPe Domain Sequences for d6t9ta_:

Sequence, based on SEQRES records: (download)

>d6t9ta_ b.47.1.2 (A:) Matriptase MTSP1 {Human (Homo sapiens) [TaxId: 9606]}
vvggtdadegewpwqvslhalgqghicgaslispnwlvsaahcyiddrgfrysdptqwta
flglhdqsqrsapgvqerrlkriishpffndftfdydiallelekpaeyssmvrpislpd
ashvfpagkaiwvtgwghtqyggtgalilqkgeirvinqttcenllpqqitprmmcvgfl
sggvdscqgdsggplssveadgrifqagvvswgdgcaqrnkpgvytrlplfrdwikentg
v

Sequence, based on observed residues (ATOM records): (download)

>d6t9ta_ b.47.1.2 (A:) Matriptase MTSP1 {Human (Homo sapiens) [TaxId: 9606]}
vvggtdadegewpwqvslhalgqghicgaslispnwlvsaahcyiddrgfrysdptqwta
flglhdqsqrsapgvqerrlkriishpffndftfdydiallelekpaeyssmvrpislpd
ashvfpagkaiwvtgwghtqyggtgalilqkgeirvinqttcenllpqqitprmmcvgfl
sggvdscqgdsggplssvedgrifqagvvswgdgcaqrnkpgvytrlplfrdwikentgv

SCOPe Domain Coordinates for d6t9ta_:

Click to download the PDB-style file with coordinates for d6t9ta_.
(The format of our PDB-style files is described here.)

Timeline for d6t9ta_: