SCOPe 2.08: Domain d6jvob_: 6jvo B:

Lineage for d6jvob_ (6jvo B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.113: Nudix [55810] (1 superfamily)
   beta(2)-alpha-beta(3)-alpha; 3 layers: alpha/beta/alpha; mixed sheet
   contains beta-grasp motif

4. Superfamily d.113.1: Nudix [55811] (8 families)

5. Family d.113.1.1: MutT-like [55812] (17 proteins)

6. Protein 7,8-dihydro-8-oxoguanine triphosphatase Hmth1 [103207] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [103208] (79 PDB entries)

8. Domain d6jvob_: 6jvo B: [394608]
   automated match to d1irya_
   protein/DNA complex; complexed with cj6
   has additional insertions and/or extensions that are not grouped together

Details for d6jvob_

PDB Entry: 6jvo, 1.9 Å

PDB Description: crystal structure of human mth1 in complex with compound mi1022

PDB Compounds: (B:) 7,8-dihydro-8-oxoguanine triphosphatase

SCOPe Domain Sequences for d6jvob_:

Sequence, based on SEQRES records:

>d6jvob_ d.113.1.1 (B:) 7,8-dihydro-8-oxoguanine triphosphatase Hmth1 {Human (Homo sapiens) [TaxId: 9606]}
gasrlytlvlvlqpqrvllgmkkrgfgagrwngfggkvqegetiedgarrelqeesgltv
dalhkvgqivfefvgepelmdvhvfctdsiqgtpvesdemrpcwfqldqipfkdmwpdds
ywfplllqkkkfhgyfkfqgqdtildytlrevdtv

Sequence, based on observed residues (ATOM records):

>d6jvob_ d.113.1.1 (B:) 7,8-dihydro-8-oxoguanine triphosphatase Hmth1 {Human (Homo sapiens) [TaxId: 9606]}
gasrlytlvlvlvllgmkkrgfgagrwngfggkvqegetiedgarrelqeesgltvdalh
kvgqivfefvgepelmdvhvfctdsiqgtpvesdemrpcwfqldqipfkdmwpddsywfp
lllqkkkfhgyfkfqgqdtildytlrevdtv

Timeline for d6jvob_:

• d6jvob_ first appeared in SCOPe 2.07