SCOP 1.75: Domain d1cs4b_: 1cs4 B:

Lineage for d1cs4b_ (1cs4 B:)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.58: Ferredoxin-like [54861] (59 superfamilies)
   alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2

4. Superfamily d.58.29: Nucleotide cyclase [55073] (2 families)
   common fold is elaborated with additional secondary structures

5. Family d.58.29.1: Adenylyl and guanylyl cyclase catalytic domain [55074] (5 proteins)
   Pfam PF00211
   structurally similar to the "palm" domain of DNA/RNA polymerase superfamily

6. Protein Adenylyl cyclase IIC1, domain C2a [55079] (1 species)

7. Species Rat (Rattus norvegicus) [TaxId:10116] [55080] (7 PDB entries)

8. Domain d1cs4b_: 1cs4 B: [39425]
   Other proteins in same PDB: d1cs4a_, d1cs4c1, d1cs4c2
   complexed with 101, cl, fok, gsp, mes, mg, pop; mutant

Details for d1cs4b_

PDB Entry: 1cs4, 2.5 Å

PDB Description: complex of gs-alpha with the catalytic domains of mammalian adenylyl cyclase: complex with 2'-deoxy-adenosine 3'-monophosphate, pyrophosphate and mg

PDB Compounds: (B:) type II adenylate cyclase

SCOP Domain Sequences for d1cs4b_:

Sequence, based on SEQRES records:

>d1cs4b_ d.58.29.1 (B:) Adenylyl cyclase IIC1, domain C2a {Rat (Rattus norvegicus) [TaxId: 10116]}
yhqsydcvcvmfasipdfkefytesdvnkegleclrllneiiadfddllskpkfsgveki
ktigstymaatglsaipsqehaqeperqymhigtmvefayalvgkldainkhsfndfklr
vginhgpviagvigaqkpqydiwgntvnvasrmdstgvldkiqvteetslilqtlgytct
crgiinvkgkgdlktyfvnt

Sequence, based on observed residues (ATOM records):

>d1cs4b_ d.58.29.1 (B:) Adenylyl cyclase IIC1, domain C2a {Rat (Rattus norvegicus) [TaxId: 10116]}
yhqsydcvcvmfasipdfkefytesdvnkegleclrllneiiadfddllskpkfsgveki
ktigstymaatglsairqymhigtmvefayalvgkldainkhsfndfklrvginhgpvia
gvigaqkpqydiwgntvnvasrmdstgvldkiqvteetslilqtlgytctcrgiinvkgk
gdlktyfvnt

Timeline for d1cs4b_:

• d1cs4b_ first appeared (with stable ids) in SCOP 1.55
  
• d1cs4b_ appears in SCOP 1.73
  
• d1cs4b_ appears in SCOPe 2.01
  
• d1cs4b_ appears in the current release, SCOPe 2.08