SCOPe 2.08: Domain d6si5a_: 6si5 A:

Lineage for d6si5a_ (6si5 A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.0: automated matches [196408] (1 protein)
   not a true family

6. Protein automated matches [196409] (46 species)
   not a true protein

7. Species Trypanosoma cruzi [TaxId:5693] [196823] (68 PDB entries)

8. Domain d6si5a_: 6si5 A: [391508]
   automated match to d1yhla_
   complexed with leq, so4

Details for d6si5a_

PDB Entry: 6si5, 2.1 Å

PDB Description: t. cruzi fpps in complex with 1-methyl-5-(4,5,6,7-tetrahydrothieno[3, 2-c]pyridine-5-carbonyl)pyridin-2(1h)-one

PDB Compounds: (A:) Farnesyl Diphosphate Synthase

SCOPe Domain Sequences for d6si5a_:

Sequence, based on SEQRES records:

>d6si5a_ a.128.1.0 (A:) automated matches {Trypanosoma cruzi [TaxId: 5693]}
asmerflsvydevqaflldqlqskyeidpnrarylrimmdttclggkyfrgmtvvnvaeg
flavtqhdeatkerilhdacvggwmieflqahylveddimdgsvmrrgkpcwyrfpgvtt
qcaindgiilkswtqimawhyfadrpflkdllclfqkvdyatavgqmydvtsmcdsnkld
pevaqpmttdfaeftpaiykrivkykttfytyllplvmgllvseaaasvemnlvervahl
igeyfqvqddvmdcftppeqlgkvgtdiedakcswlavtflgkanaaqvaefkanygekd
pakvavvkrlyskanlqadfaayeaevvreveslieqlkvksptfaesvavvwekthk

Sequence, based on observed residues (ATOM records):

>d6si5a_ a.128.1.0 (A:) automated matches {Trypanosoma cruzi [TaxId: 5693]}
asmerflsvydevqaflldqlqskyeidpnrarylrimmdttclggkyfrgmtvvnvaeg
flavtqhdeatkerilhdacvggwmieflqahylveddimdgsvmrrgkpcwyrfpgvtt
qcaindgiilkswtqimawhyfadrpflkdllclfqkvdyatavgqmydvtsmcdsnkld
pevaqpmttdfaeftpaiykrivkykttfytyllplvmgllvseaaasvemnlvervahl
igeyfqvqddvmdcftppeqgtdiedakcswlavtflgkanaaqvaefkanygekdpakv
avvkrlyskanlqadfaayeaevvreveslieqlkvksptfaesvavvwekthk

Timeline for d6si5a_:

• d6si5a_ first appeared in SCOPe 2.07