Lineage for d6scma_ (6scm A:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2338409Fold a.117: Ras GEF [48365] (1 superfamily)
    multihelical
  4. 2338410Superfamily a.117.1: Ras GEF [48366] (1 family) (S)
  5. 2338411Family a.117.1.1: Ras GEF [48367] (2 proteins)
  6. 2338412Protein Son of sevenless protein homolog 1 (sos-1) [48368] (1 species)
  7. 2338413Species Human (Homo sapiens) [TaxId:9606] [48369] (60 PDB entries)
    Uniprot Q07889 189-1046
  8. 2338424Domain d6scma_: 6scm A: [391485]
    automated match to d1nvus_
    complexed with edo, imd, l7h

Details for d6scma_

PDB Entry: 6scm (more details), 1.87 Å

PDB Description: sos1 in complex with inhibitor bi-3406
PDB Compounds: (A:) Son of sevenless homolog 1

SCOPe Domain Sequences for d6scma_:

Sequence, based on SEQRES records: (download)

>d6scma_ a.117.1.1 (A:) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
eeqmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnf
vrtflttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiq
pvqlrvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkia
rdngpghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpse
lvgsvwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvfq
elnnfngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsin
ppcvpffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrv
esdikrffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrps

Sequence, based on observed residues (ATOM records): (download)

>d6scma_ a.117.1.1 (A:) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
eeqmrlpsadvyrfaepdseeniifeenmipiikagtviklierltyhmyadpnfvrtfl
ttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpvqlr
vlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiahnitf
qsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpselvgsvwtkedk
einspnllkmirhttnltlwfekcivetenleervavvsriieilqvfqelnnfngvlev
vsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinppcvpffgiyl
tnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrvesdikrffenl
npmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrps

SCOPe Domain Coordinates for d6scma_:

Click to download the PDB-style file with coordinates for d6scma_.
(The format of our PDB-style files is described here.)

Timeline for d6scma_: