SCOPe 2.08: Domain d6rija_: 6rij A:

Lineage for d6rija_ (6rij A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (417 PDB entries)
   Uniprot P24941

8. Domain d6rija_: 6rij A: [391448]
   Other proteins in same PDB: d6rijb1, d6rijb2, d6rijd1, d6rijd2
   automated match to d1gy3a_
   complexed with gol, k4w, na

Details for d6rija_

PDB Entry: 6rij, 2.2 Å

PDB Description: cdk2/cyclin a2 in complex with open-ring 5-nitrosopyrimidine inhibitor lc436

PDB Compounds: (A:) cyclin-dependent kinase 2

SCOPe Domain Sequences for d6rija_:

Sequence; same for both SEQRES and ATOM records:

>d6rija_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvt

Timeline for d6rija_:

• d6rija_ first appeared in SCOPe 2.07