Lineage for d6x5pa_ (6x5p A:)

  1. Root: SCOPe 2.07
  2. 2352458Class b: All beta proteins [48724] (178 folds)
  3. 2404157Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2404158Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2404432Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)
  6. 2404660Protein Coagulation factor IXa, protease domain [50583] (2 species)
  7. 2404661Species Human (Homo sapiens) [TaxId:9606] [50585] (20 PDB entries)
  8. 2404677Domain d6x5pa_: 6x5p A: [388404]
    Other proteins in same PDB: d6x5pb_
    automated match to d5tnta_
    complexed with cit, gol, uqd

Details for d6x5pa_

PDB Entry: 6x5p (more details), 2 Å

PDB Description: discovery of hydroxy pyrimidine factor ixa inhibitors
PDB Compounds: (A:) coagulation factor ix

SCOPe Domain Sequences for d6x5pa_:

Sequence, based on SEQRES records: (download)

>d6x5pa_ b.47.1.2 (A:) Coagulation factor IXa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
vvggedakpgqfpwqvvlngkvdafcggsivnekwivtaahcvetgvkitvvagehniee
tehteqkrnviriiphhnynaainkynhdialleldeplvlnsyvtpiciadkeytnifl
kfgsgyvsgwgrvfhkgasalvlqylrvplvdratclrstkftiynnmfcagfheggrds
cqgdsggphvtevegtsfltgiiswgeecamkgkygiytkvsryvnwikektkl

Sequence, based on observed residues (ATOM records): (download)

>d6x5pa_ b.47.1.2 (A:) Coagulation factor IXa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
vvggedakpgqfpwqvvlngkvdafcggsivnekwivtaahcvevkitvvagehnieete
hteqkrnviriiphhnynaainkynhdialleldeplvlnsyvtpiciadkeytniflkf
gsgyvsgwgrvfhkgasalvlqylrvplvdratclrstkftiynnmfcagfheggrdscq
gdsggphvtevegtsfltgiiswgeecamkgkygiytkvsryvnwikektkl

SCOPe Domain Coordinates for d6x5pa_:

Click to download the PDB-style file with coordinates for d6x5pa_.
(The format of our PDB-style files is described here.)

Timeline for d6x5pa_: