SCOPe 2.06: Domain d1otpa3: 1otp A:336-440

Lineage for d1otpa3 (1otp A:336-440)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.41: alpha/beta-Hammerhead [54664] (5 superfamilies)
   core: beta-BETA-alpha-beta-BETA-beta-alpha; contains a beta-hammerhead motif similar to that in barrel-sandwich hybrids

4. Superfamily d.41.3: Pyrimidine nucleoside phosphorylase C-terminal domain [54680] (2 families)

5. Family d.41.3.1: Pyrimidine nucleoside phosphorylase C-terminal domain [54681] (2 proteins)

6. Protein Thymidine phosphorylase [54682] (2 species)

7. Species Escherichia coli [TaxId:562] [54683] (7 PDB entries)

8. Domain d1otpa3: 1otp A:336-440 [38622]
   Other proteins in same PDB: d1otpa1, d1otpa2, d1otpa4

Details for d1otpa3

PDB Entry: 1otp, 2.8 Å

PDB Description: structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase

PDB Compounds: (A:) thymidine phosphorylase

SCOPe Domain Sequences for d1otpa3:

Sequence; same for both SEQRES and ATOM records:

>d1otpa3 d.41.3.1 (A:336-440) Thymidine phosphorylase {Escherichia coli [TaxId: 562]}
tamltkavyadtegfvsemdtralgmavvamgggrrqasdtidysvgftdmarlgdqvdg
qrplavihakdennwqeaakavkaaikladkapestptvyrrise

Timeline for d1otpa3:

• d1otpa3 first appeared (with stable ids) in SCOP 1.55, called d1otp_3
  
• d1otpa3 appears in SCOPe 2.05
  
• d1otpa3 appears in SCOPe 2.07
  
• d1otpa3 appears in the current release, SCOPe 2.08