SCOP 1.63: Domain d1otp_3: 1otp 336-440

Lineage for d1otp_3 (1otp 336-440)

1. Root: SCOP 1.63

2. Class d: Alpha and beta proteins (a+b) [53931] (224 folds)

3. Fold d.41: alpha/beta-Hammerhead [54664] (5 superfamilies)
   core: beta-BETA-alpha-beta-BETA-beta-alpha; contains a beta-hammerhead motif similar to that in barrel-sandwich hybrids

4. Superfamily d.41.3: Pyrimidine nucleoside phosphorylase C-terminal domain [54680] (1 family)

5. Family d.41.3.1: Pyrimidine nucleoside phosphorylase C-terminal domain [54681] (2 proteins)

6. Protein Thymidine phosphorylase [54682] (1 species)

7. Species Escherichia coli [TaxId:562] [54683] (4 PDB entries)

8. Domain d1otp_3: 1otp 336-440 [38622]
   Other proteins in same PDB: d1otp_1, d1otp_2

Details for d1otp_3

PDB Entry: 1otp, 2.8 Å

PDB Description: structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase

SCOP Domain Sequences for d1otp_3:

Sequence; same for both SEQRES and ATOM records:

>d1otp_3 d.41.3.1 (336-440) Thymidine phosphorylase {Escherichia coli}
tamltkavyadtegfvsemdtralgmavvamgggrrqasdtidysvgftdmarlgdqvdg
qrplavihakdennwqeaakavkaaikladkapestptvyrrise

Timeline for d1otp_3:

• d1otp_3 first appeared (with stable ids) in SCOP 1.55
  
• d1otp_3 appears in SCOP 1.61
  
• d1otp_3 appears in SCOP 1.65
  
• d1otp_3 appears in the current release, SCOPe 2.08, called d1otpa3