Lineage for d6opla_ (6opl A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2841375Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
    has additional subdomain(s) that are not in the common domain
  6. 2841687Protein Biliverdin IX beta reductase [63931] (1 species)
    Histidine in the active site instead of the Tyr-Lys dyad
  7. 2841688Species Human (Homo sapiens) [TaxId:9606] [63932] (8 PDB entries)
  8. 2841693Domain d6opla_: 6opl A: [384678]
    automated match to d1hdoa_
    complexed with nap; mutant

Details for d6opla_

PDB Entry: 6opl (more details), 1.37 Å

PDB Description: human biliverdin ix beta reductase q14r mutant: nadp complex
PDB Compounds: (A:) Flavin reductase (NADPH)

SCOPe Domain Sequences for d6opla_:

Sequence; same for both SEQRES and ATOM records: (download)

>d6opla_ c.2.1.2 (A:) Biliverdin IX beta reductase {Human (Homo sapiens) [TaxId: 9606]}
mavkkiaifgatgrtglttlaqavqagyevtvlvrdssrlpsegprpahvvvgdvlqaad
vdktvagqdavivllgtrndlspttvmsegarnivaamkahgvdkvvactsafllwdptk
vpprlqavtddhirmhkvlresglkyvavmpphigdqpltgaytvtldgrgpsrviskhd
lghfmlrclttdeydghstypshqy

SCOPe Domain Coordinates for d6opla_:

Click to download the PDB-style file with coordinates for d6opla_.
(The format of our PDB-style files is described here.)

Timeline for d6opla_: