SCOPe 2.08: Domain d6rcha_: 6rch A:

Lineage for d6rcha_ (6rch A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Casein kinase-1, CK1 [56139] (4 species)
   OPK group; CKI subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [224941] (25 PDB entries)

8. Domain d6rcha_: 6rch A: [382764]
   automated match to d1ckia_
   complexed with edo, k0b, na, so4

Details for d6rcha_

PDB Entry: 6rch, 1.45 Å

PDB Description: crystal structure of casein kinase i isoform delta (ck1 delta) complexed with sr4133 inhibitor

PDB Compounds: (A:) Casein kinase I isoform delta

SCOPe Domain Sequences for d6rcha_:

Sequence; same for both SEQRES and ATOM records:

>d6rcha_ d.144.1.7 (A:) Casein kinase-1, CK1 {Human (Homo sapiens) [TaxId: 9606]}
elrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmqg
gvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihs
knfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtaryas
inthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievlc
kgypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlk

Timeline for d6rcha_:

• d6rcha_ first appeared in SCOPe 2.07