SCOPe 2.07: Domain d6vpkc_: 6vpk C:

Lineage for d6vpkc_ (6vpk C:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (212 PDB entries)

8. Domain d6vpkc_: 6vpk C: [382563]
   automated match to d3q95b_
   complexed with rl4; mutant

Details for d6vpkc_

PDB Entry: 6vpk, 1.7 Å

PDB Description: estrogen receptor alpha ligand binding domain y537s mutant in complex with a methylated lasofoxifene derivative that enhances estrogen receptor alpha nuclear resonance time

PDB Compounds: (C:) Estrogen receptor

SCOPe Domain Sequences for d6vpkc_:

Sequence, based on SEQRES records:

>d6vpkc_ a.123.1.1 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpg
fvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifd
mllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtl
ihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvplsdlllemlda
hrlh

Sequence, based on observed residues (ATOM records):

>d6vpkc_ a.123.1.1 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpsmmglltnladrelvhminwakrvpgfvdl
tlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdmlla
tssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlihlm
akagltlqqqhqrlaqlllilshirhmsnkgmehlysmplsdlllemldahrlh

Timeline for d6vpkc_:

• d6vpkc_ is new in SCOPe 2.07-stable
  
• d6vpkc_ appears in the current release, SCOPe 2.08