SCOPe 2.08: Domain d6i82a1: 6i82 A:705-1012

Lineage for d6i82a1 (6i82 A:705-1012)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d6i82a1: 6i82 A:705-1012 [382089]
   Other proteins in same PDB: d6i82a2
   automated match to d3b2tb_
   complexed with cl, edo, fmt, h6w

Details for d6i82a1

PDB Entry: 6i82, 2.05 Å

PDB Description: crystal structure of partially phosphorylated ret v804m tyrosine kinase domain complexed with pdd00018412

PDB Compounds: (A:) proto-oncogene tyrosine-protein kinase receptor ret

SCOPe Domain Sequences for d6i82a1:

Sequence, based on SEQRES records:

>d6i82a1 d.144.1.0 (A:705-1012) automated matches {Human (Homo sapiens) [TaxId: 9606]}
svdafkiledpkwefprknlvlgktlgegefgkvvkatafhlkgragyttvavkmlkena
spselrdllsefnvlkqvnhphviklygacsqdgplllimeyakygslrgflresrkvgp
gylgsggsrnsssldhpderaltmgdlisfawqisqgmqylaemklvhrdlaarnilvae
grkmkisdfglsrdvyeedsyvkrsqgripvkwmaieslfdhiyttqsdvwsfgvllwei
vtlggnpypgipperlfnllktghrmerpdncseemyrlmlqcwkqepdkrpvfadiskd
lekmmvkr

Sequence, based on observed residues (ATOM records):

>d6i82a1 d.144.1.0 (A:705-1012) automated matches {Human (Homo sapiens) [TaxId: 9606]}
svdafkiledpkwefprknlvlgktlgegefgkvvkatafhlkgragyttvavkmlkena
spselrdllsefnvlkqvnhphviklygacsqdgplllimeyakygslrgflreseralt
mgdlisfawqisqgmqylaemklvhrdlaarnilvaegrkmkisdfglsrdvyqgripvk
wmaieslfdhiyttqsdvwsfgvllweivtlggnpypgipperlfnllktghrmerpdnc
seemyrlmlqcwkqepdkrpvfadiskdlekmmvkr

Timeline for d6i82a1:

• d6i82a1 first appeared in SCOPe 2.07