SCOPe 2.08: Domain d6lz9b_: 6lz9 B:

Lineage for d6lz9b_ (6lz9 B:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Hepatocyte growth factor, HGF [110239] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [110240] (3 PDB entries)
   Uniprot P14210 495-728 ! Uniprot P14210 495-722

8. Domain d6lz9b_: 6lz9 B: [382086]
   Other proteins in same PDB: d6lz9h_, d6lz9l1, d6lz9l2
   automated match to d1si5h_

Details for d6lz9b_

PDB Entry: 6lz9, 2.8 Å

PDB Description: t8e4 antibody fab complexed with the active form of hgf

PDB Compounds: (B:) hepatocyte growth factor

SCOPe Domain Sequences for d6lz9b_:

Sequence, based on SEQRES records:

>d6lz9b_ b.47.1.2 (B:) Hepatocyte growth factor, HGF {Human (Homo sapiens) [TaxId: 9606]}
vvngiptrtnigwmvslryrnkhicggslikeswvltarqcfpsrdlkdyeawlgihdvh
grgdekskqvlqvsqlvygpegsdlvlmklarpavlddfvstidlpnygctipektscsv
ygwgytglinydgllrvahlyimgnekcsqhhrgkvtlqeseicagaekigsgpcegdyg
gplvceqhkmrmvlgvivpgrgcaipnrpgifvrvayyakwihkiiltykvp

Sequence, based on observed residues (ATOM records):

>d6lz9b_ b.47.1.2 (B:) Hepatocyte growth factor, HGF {Human (Homo sapiens) [TaxId: 9606]}
vvngiptrtnigwmvslryrnkhicggslikeswvltarqcfpsrdlkdyeawlgihdvh
grgdekskqvlqvsqlvygpegsdlvlmklarpavlddfvstidlpnygctipektscsv
ygwgytglinydgllrvahlyimgnekcsqlqeseicagaigsgpcegdyggplvceqhk
mrmvlgvivpgrgcaipnrpgifvrvayyakwihkiiltykvp

Timeline for d6lz9b_:

• d6lz9b_ first appeared in SCOPe 2.07