SCOPe 2.07: Domain d6u67b1: 6u67 B:171-321

Lineage for d6u67b1 (6u67 B:171-321)

1. Root: SCOPe 2.07

2. Class f: Membrane and cell surface proteins and peptides [56835] (60 folds)

3. Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
   multi-helical domains of various folds which is thought to unfold in the membrane

4. Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
   PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain

5. Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
   Pfam PF00452

6. Protein automated matches [190236] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188722] (88 PDB entries)

8. Domain d6u67b1: 6u67 B:171-321 [381917]
   Other proteins in same PDB: d6u67b2
   automated match to d2kbwa_
   complexed with bnl, q01

Details for d6u67b1

PDB Entry: 6u67, 1.84 Å

PDB Description: mcl-1 bound to compound 24

PDB Compounds: (B:) Induced myeloid leukemia cell differentiation protein Mcl-1

SCOPe Domain Sequences for d6u67b1:

Sequence; same for both SEQRES and ATOM records:

>d6u67b1 f.1.4.1 (B:171-321) automated matches {Human (Homo sapiens) [TaxId: 9606]}
edelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqg
mlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepl
aesitdvlvrtkrdwlvkqrgwdgfveffhv

Timeline for d6u67b1:

• d6u67b1 is new in SCOPe 2.07-stable
  
• d6u67b1 appears in the current release, SCOPe 2.08