SCOPe 2.07: Domain d6o4ua_: 6o4u A:

Lineage for d6o4ua_ (6o4u A:)

1. Root: SCOPe 2.07

2. Class f: Membrane and cell surface proteins and peptides [56835] (60 folds)

3. Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
   multi-helical domains of various folds which is thought to unfold in the membrane

4. Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
   PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain

5. Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
   Pfam PF00452

6. Protein automated matches [190236] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188722] (88 PDB entries)

8. Domain d6o4ua_: 6o4u A: [381719]
   automated match to d2kbwa_
   complexed with lmv

Details for d6o4ua_

PDB Entry: 6o4u, 1.7 Å

PDB Description: co-crystal structure of mcl1 with inhibitor

PDB Compounds: (A:) Induced myeloid leukemia cell differentiation protein Mcl-1

SCOPe Domain Sequences for d6o4ua_:

Sequence, based on SEQRES records:

>d6o4ua_ f.1.4.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
delyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqgm
lrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepla
esitdvlvrtkrdwlvkqrgwdgfveffhv

Sequence, based on observed residues (ATOM records):

>d6o4ua_ f.1.4.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
delyrqsleiisrylreqatgakdgrsgatsrkaletlrrvgdgvqrnhetafqgmlrkl
dikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescieplaesit
dvlvrtkrdwlvkqrgwdgfveffhv

Timeline for d6o4ua_:

• d6o4ua_ is new in SCOPe 2.07-stable
  
• d6o4ua_ appears in the current release, SCOPe 2.08