SCOPe 2.08: Domain d6mz0b1: 6mz0 B:162-350

Lineage for d6mz0b1 (6mz0 B:162-350)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.136: Phospholipase D/nuclease [56023] (1 superfamily)
   beta-alpha-beta-alpha-beta-alpha-beta(4)-alpha; mixed sheet: order 1765234

4. Superfamily d.136.1: Phospholipase D/nuclease [56024] (6 families)

5. Family d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1 [69815] (2 proteins)

6. Protein Tyrosyl-DNA phosphodiesterase TDP1 [69816] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69817] (36 PDB entries)

8. Domain d6mz0b1: 6mz0 B:162-350 [376473]
   automated match to d1qzqa1
   protein/DNA complex; complexed with edo, k7a

Details for d6mz0b1

PDB Entry: 6mz0, 1.97 Å

PDB Description: crystal structure of tdp1 catalytic domain in complex with compound xz530

PDB Compounds: (B:) tyrosyl-DNA phosphodiesterase 1

SCOPe Domain Sequences for d6mz0b1:

Sequence; same for both SEQRES and ATOM records:

>d6mz0b1 d.136.1.3 (B:162-350) Tyrosyl-DNA phosphodiesterase TDP1 {Human (Homo sapiens) [TaxId: 9606]}
npfqfyltrvsgvkpkynsgalhikdilsplfgtlvssaqfnycfdvdwlvkqyppefrk
kpillvhgdkreakahlhaqakpyenislcqakldiafgthhtkmmlllyeeglrvviht
snlihadwhqktqgiwlsplypriadgthksgespthfkadlisylmaynapslkewidv
ihkhdlset

Timeline for d6mz0b1:

• d6mz0b1 first appeared in SCOPe 2.07