Lineage for d1e7va3 (1e7v A:144-321)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2158219Fold d.15: beta-Grasp (ubiquitin-like) [54235] (14 superfamilies)
    core: beta(2)-alpha-beta(2); mixed beta-sheet 2143
  4. 2158220Superfamily d.15.1: Ubiquitin-like [54236] (11 families) (S)
  5. 2159292Family d.15.1.5: Ras-binding domain, RBD [54263] (14 protein domains)
    contains Pfam PF00788 and Pfam PF02196
  6. 2159312Protein Phoshoinositide 3-kinase (PI3K) [54274] (2 species)
    includes parts of the flanking linkers
  7. 2159372Species Pig (Sus scrofa) [TaxId:9823] [54275] (6 PDB entries)
  8. 2159376Domain d1e7va3: 1e7v A:144-321 [37632]
    Other proteins in same PDB: d1e7va1, d1e7va2, d1e7va4, d1e7va5
    complexed with ly2

Details for d1e7va3

PDB Entry: 1e7v (more details), 2.4 Å

PDB Description: Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine
PDB Compounds: (A:) phosphatidylinositol 3-kinase catalytic subunit

SCOPe Domain Sequences for d1e7va3:

Sequence, based on SEQRES records: (download)

>d1e7va3 d.15.1.5 (A:144-321) Phoshoinositide 3-kinase (PI3K) {Pig (Sus scrofa) [TaxId: 9823]}
seetlafqrqlnaligydvtdvsnvhddeleftrrrlvtprmaevagrdpklyamhpwvt
skplpeyllkkitnncvfivihrsttsqtikvsaddtpgtilqsfftkmakkkslmdipe
sqnerdfvlrvcgrdeylvgetpiknfqwvrqclkngeeihlvldtppdpaldevrke

Sequence, based on observed residues (ATOM records): (download)

>d1e7va3 d.15.1.5 (A:144-321) Phoshoinositide 3-kinase (PI3K) {Pig (Sus scrofa) [TaxId: 9823]}
seetlafqrqlnaligydvtdvsnvhddeleftrrrlvtprmaevagrdpklyamhpwvt
skplpeyllkkitnncvfivihrsttsqtikvsaddtpgtilqsfftkmadfvlrvcgrd
eylvgetpiknfqwvrqclkngeeihlvldtppdpaldevrke

SCOPe Domain Coordinates for d1e7va3:

Click to download the PDB-style file with coordinates for d1e7va3.
(The format of our PDB-style files is described here.)

Timeline for d1e7va3: