SCOPe 2.08: Domain d6hveb_: 6hve B:

Lineage for d6hveb_ (6hve B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein c-src tyrosine kinase [56155] (3 species)
   PTK group; Src subfamily; non-membrane spanning protein tyrosine kinase

7. Species Chicken (Gallus gallus) [TaxId:9031] [56157] (56 PDB entries)

8. Domain d6hveb_: 6hve B: [376047]
   automated match to d2hwoa_
   complexed with guw

Details for d6hveb_

PDB Entry: 6hve, 1.9 Å

PDB Description: kinase domain of csrc in complex with compound 9

PDB Compounds: (B:) Proto-oncogene tyrosine-protein kinase Src

SCOPe Domain Sequences for d6hveb_:

Sequence, based on SEQRES records:

>d6hveb_ d.144.1.7 (B:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
daweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkkl
rheklvqlyavvseepiyivmeymskgclldflkgemgkylrlpqlvdmaaqiasgmayv
ermnyvhrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaalyg
rftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcq
cwrkdpeerptfeylqafledyftstepqyqpgenl

Sequence, based on observed residues (ATOM records):

>d6hveb_ d.144.1.7 (B:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
daweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpaqvmkklrheklvqlyav
vseepiyivmeymskgclldflkgemgkylrlpqlvdmaaqiasgmayvermnyvhrdlr
aanilvgenlvckvadfpikwtapeaalygrftiksdvwsfgilltelttkgrvpypgmv
nrevldqvergyrmpcppecpeslhdlmcqcwrkdpeerptfeylqafledyftstepqy
qpgenl

Timeline for d6hveb_:

• d6hveb_ first appeared in SCOPe 2.07