SCOPe 2.06: Domain d2fita_: 2fit A:

Lineage for d2fita_ (2fit A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.13: HIT-like [54196] (2 superfamilies)
   alpha-beta(3)-alpha-beta(2); 3 layers: alpha/beta/alpha

4. Superfamily d.13.1: HIT-like [54197] (5 families)

5. Family d.13.1.1: HIT (HINT, histidine triad) family of protein kinase-interacting proteins [54198] (8 proteins)
   Pfam PF01230
   topologically similar to the N-terminal domain of protein kinases

6. Protein FHIT (fragile histidine triad protein) [54201] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [54202] (8 PDB entries)

8. Domain d2fita_: 2fit A: [37500]
   complexed with fru, so4

Details for d2fita_

PDB Entry: 2fit, 1.9 Å

PDB Description: fhit (fragile histidine triad protein)

PDB Compounds: (A:) fragile histidine protein

SCOPe Domain Sequences for d2fita_:

Sequence, based on SEQRES records:

>d2fita_ d.13.1.1 (A:) FHIT (fragile histidine triad protein) {Human (Homo sapiens) [TaxId: 9606]}
sfrfgqhlikpsvvflktelsfalvnrkpvvpghvlvcplrpverfhdlrpdevadlfqt
tqrvgtvvekhfhgtsltfsmqdgpeagqtvkhvhvhvlprkagdfhrndsiyeelqkhd
kedfpaswrseeemaaeaaalrvyfq

Sequence, based on observed residues (ATOM records):

>d2fita_ d.13.1.1 (A:) FHIT (fragile histidine triad protein) {Human (Homo sapiens) [TaxId: 9606]}
sfrfgqhlikpsvvflktelsfalvnrkpvvpghvlvcplrpverfhdlrpdevadlfqt
tqrvgtvvekhfhgtsltfsmqdgpeagqtvkhvhvhvlprkagdfhfpaswrseeemaa
eaaalrvyfq

Timeline for d2fita_:

• d2fita_ first appeared (with stable ids) in SCOP 1.55, called d2fit__
  
• d2fita_ appears in SCOPe 2.05
  
• d2fita_ appears in SCOPe 2.07
  
• d2fita_ appears in the current release, SCOPe 2.08