SCOPe 2.08: Domain d6kdfb_: 6kdf B:

Lineage for d6kdfb_ (6kdf B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families)
   the constituent families form similar dimers

5. Family c.77.1.0: automated matches [191423] (1 protein)
   not a true family

6. Protein automated matches [190603] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [329721] (12 PDB entries)

8. Domain d6kdfb_: 6kdf B: [374648]
   Other proteins in same PDB: d6kdfc2, d6kdfd2, d6kdfe2, d6kdff2, d6kdfh2, d6kdfj2, d6kdfl2, d6kdfn2, d6kdfp2
   automated match to d3blxc_

Details for d6kdfb_

PDB Entry: 6kdf, 3.05 Å

PDB Description: crystal structure of the alpha beta heterodimer of human idh3 in apo form.

PDB Compounds: (B:) Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

SCOPe Domain Sequences for d6kdfb_:

Sequence, based on SEQRES records:

>d6kdfb_ c.77.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ggvqtvtlipgdgigpeisaavmkifdaakapiqweernvtaiqgpggkwmipseakesm
dknkmglkgplktpiaaghpsmnlllrktfdlyanvrpcvsiegyktpytdvnivtiren
tegeysgiehvivdgvvqsiklitegaskriaefafeyarnnhrsnvtavhkanimrmsd
glflqkcrevaesckdikfnemyldtvclnmvqdpsqfdvlvmpnlygdilsdlcaglig
glgvtpsgnigangvaifesvhgtapdiagkdmanptalllsavmmlrhmglfdhaarie
aacfatikdgksltkdlggnakcsdfteeicrrvkd

Sequence, based on observed residues (ATOM records):

>d6kdfb_ c.77.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ggvqtvtlipgdgigpeisaavmkifdaakapiqweernvtaiqgpwmipseakesmdkn
kmglkgplktpiaaghpsmnlllrktfdlyanvrpcvsiegyktpytdvnivtirenteg
eysgiehvivdgvvqsiklitegaskriaefafeyarnnhrsnvtavhkanimrmsdglf
lqkcrevaesckdikfnemyldtvclnmvqdpsqfdvlvmpnlygdilsdlcagligglg
vtpsgnigangvaifesvhgtapdiagkdmanptalllsavmmlrhmglfdhaarieaac
fatikdgksltkdlggnakcsdfteeicrrvkd

Timeline for d6kdfb_:

• d6kdfb_ first appeared in SCOPe 2.07