SCOPe 2.08: Domain d6hwmf1: 6hwm F:2-194

Lineage for d6hwmf1 (6hwm F:2-194)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.14: ClpP/crotonase [52095] (1 superfamily)
   core: 4 turns of (beta-beta-alpha)n superhelix

4. Superfamily c.14.1: ClpP/crotonase [52096] (5 families)

5. Family c.14.1.0: automated matches [191346] (1 protein)
   not a true family

6. Protein automated matches [190246] (71 species)
   not a true protein

7. Species Thermus thermophilus [TaxId:274] [374087] (2 PDB entries)

8. Domain d6hwmf1: 6hwm F:2-194 [374114]
   Other proteins in same PDB: d6hwmb2, d6hwme2, d6hwmf2
   automated match to d5g1sq_
   complexed with bo2, peg

Details for d6hwmf1

PDB Entry: 6hwm, 2.7 Å

PDB Description: structure of thermus thermophilus clpp in complex with bortezomib

PDB Compounds: (F:) ATP-dependent Clp protease proteolytic subunit

SCOPe Domain Sequences for d6hwmf1:

Sequence, based on SEQRES records:

>d6hwmf1 c.14.1.0 (F:2-194) automated matches {Thermus thermophilus [TaxId: 274]}
vipyvieqtargervydiysrllkdriiflgtpidaqvanvvvaqllfldaqnpnqeikl
yinspggevdaglaiydtmqfvrapvstivigmaasmaavilaagekgrryalphakvmi
hqpwggvrgtasdiaiqaqeilkakkllneilakhtgqplekvekdtdrdyylsaqeale
yglidqvvtreea

Sequence, based on observed residues (ATOM records):

>d6hwmf1 c.14.1.0 (F:2-194) automated matches {Thermus thermophilus [TaxId: 274]}
vipyviervydiysrllkdriiflgtpidaqvanvvvaqllfldaqnpnqeiklyinspg
gevdaglaiydtmqfvrapvstivigmaasmaavilaagekgrryalphakvmihqpwgg
vrgtasdiaiqaqeilkakkllneilakhtgqplekvekdtdrdyylsaqealeyglidq
vvtreea

Timeline for d6hwmf1:

• d6hwmf1 first appeared in SCOPe 2.07