SCOPe 2.07: Domain d6hmpa_: 6hmp A:

Lineage for d6hmpa_ (6hmp A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Casein kinase-1, CK1 [56139] (4 species)
   OPK group; CKI subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [224941] (25 PDB entries)

8. Domain d6hmpa_: 6hmp A: [373962]
   automated match to d1ckia_
   complexed with gew, po4

Details for d6hmpa_

PDB Entry: 6hmp, 2.04 Å

PDB Description: crystal structure of human casein kinase i delta in complex with a photoswitchable 2-azoimidazole-based inhibitor (compound 3)

PDB Compounds: (A:) Casein kinase I isoform delta

SCOPe Domain Sequences for d6hmpa_:

Sequence, based on SEQRES records:

>d6hmpa_ d.144.1.7 (A:) Casein kinase-1, CK1 {Human (Homo sapiens) [TaxId: 9606]}
ryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmqggvgipt
irwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihsknfihr
dvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtaryasinthlg
ieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievlckgypse
fatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlk

Sequence, based on observed residues (ATOM records):

>d6hmpa_ d.144.1.7 (A:) Casein kinase-1, CK1 {Human (Homo sapiens) [TaxId: 9606]}
ryrlgrkigsgsfgdiylgtdiaaeevaiklecvktkhpqlhieskiykmmqggvgipti
rwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihsknfihrd
vkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtaryasinthlgi
eqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievlckgypsef
atylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlk

Timeline for d6hmpa_:

• d6hmpa_ is new in SCOPe 2.07-stable
  
• d6hmpa_ appears in the current release, SCOPe 2.08