Lineage for d6hmpb_ (6hmp B:)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. Protein Casein kinase-1, CK1 [56139] (4 species)
    OPK group; CKI subfamily; serine/threonine kinase
  7. Species Human (Homo sapiens) [TaxId:9606] [224941] (25 PDB entries)
  8. Domain d6hmpb_: 6hmp B: [373939]
    automated match to d1ckia_
    complexed with gew, po4

Details for d6hmpb_

PDB Entry: 6hmp (more details), 2.04 Å

PDB Description: crystal structure of human casein kinase i delta in complex with a photoswitchable 2-azoimidazole-based inhibitor (compound 3)
PDB Compounds: (B:) Casein kinase I isoform delta

SCOPe Domain Sequences for d6hmpb_:

Sequence, based on SEQRES records: (download)

>d6hmpb_ d.144.1.7 (B:) Casein kinase-1, CK1 {Human (Homo sapiens) [TaxId: 9606]}
melrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmq
ggvgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyih
sknfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtarya
sinthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievl
ckgypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnml

Sequence, based on observed residues (ATOM records): (download)

>d6hmpb_ d.144.1.7 (B:) Casein kinase-1, CK1 {Human (Homo sapiens) [TaxId: 9606]}
melrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvhpqlhieskiykmmqggv
giptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihskn
fihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtaryasin
thlgieqsrrddleslgyvlmyfnlgslpwqrisekkmstpievlckgypsefatylnfc
rslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnml

SCOPe Domain Coordinates for d6hmpb_ are not available.

Timeline for d6hmpb_:

Domains from other chains:
(mouse over for more information)
d6hmpa_