Lineage for d6agxc_ (6agx C:)

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2586062Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2586063Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2586210Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2589707Protein automated matches [190091] (20 species)
    not a true protein
  7. 2589831Species Human (Homo sapiens) [TaxId:9606] [188447] (892 PDB entries)
  8. 2591050Domain d6agxc_: 6agx C: [373106]
    automated match to d3b2ta_
    complexed with 9wx

Details for d6agxc_

PDB Entry: 6agx (more details), 2.95 Å

PDB Description: the cocrystal structure of fgfr2 bound with compound 14 harboring 5h- pyrrolo[2,3-b]pyrazine scaffold
PDB Compounds: (C:) Fibroblast growth factor receptor 2

SCOPe Domain Sequences for d6agxc_:

Sequence, based on SEQRES records: (download)

>d6agxc_ d.144.1.7 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
elpedpkwefprdkltlgkplgegcfgqvvmaeavgidkdkpkeavtvavkmlkddatek
dlsdlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylrarrppgmey
sydinrvpeeqmtfkdlvsctyqlargmeylasqkcihrdltarnvlvtennvmkiadfg
lardinnidyykkttngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypg
ipveelfkllkeghrmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltlt

Sequence, based on observed residues (ATOM records): (download)

>d6agxc_ d.144.1.7 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
elpedpkwefprdkltlgkplgegcfgqvvmaeavgidkdkpkeavtvavkmlkddatek
dlsdlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylrarrpnrvpe
eqmtfkdlvsctyqlargmeylasqkcihrdltarnvlvtennvmkiadfglardiykkt
tngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypgipveelfkllkegh
rmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltlt

SCOPe Domain Coordinates for d6agxc_:

Click to download the PDB-style file with coordinates for d6agxc_.
(The format of our PDB-style files is described here.)

Timeline for d6agxc_: