SCOPe 2.08: Domain d6nx8b_: 6nx8 B:

Lineage for d6nx8b_ (6nx8 B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.88: Glutaminase/Asparaginase [53773] (1 superfamily)
   consists of two non-similar alpha/beta domains, 3 layers (a/b/a) each
   Domain 1 has mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest; left-handed crossover connection between strands 4 and 5
   Domain 2 has parallel beta-sheet of 4 strands, order 1234

4. Superfamily c.88.1: Glutaminase/Asparaginase [53774] (2 families)

5. Family c.88.1.1: Glutaminase/Asparaginase [53775] (4 proteins)
   automatically mapped to Pfam PF00710

6. Protein Asparaginase type II [53776] (5 species)

7. Species Escherichia coli [TaxId:562] [53777] (42 PDB entries)

8. Domain d6nx8b_: 6nx8 B: [372694]
   Other proteins in same PDB: d6nx8a2
   automated match to d1jaza_
   complexed with acy, cit; mutant

Details for d6nx8b_

PDB Entry: 6nx8, 1.85 Å

PDB Description: ecaii(d90t,k162t) mutant in complex with citrate at ph 6.2

PDB Compounds: (B:) L-asparaginase 2

SCOPe Domain Sequences for d6nx8b_:

Sequence, based on SEQRES records:

>d6nx8b_ c.88.1.1 (B:) Asparaginase type II {Escherichia coli [TaxId: 562]}
lpnitilatggtiagggdsatksnytvgkvgvenlvnavpqlkdianvkgeqvvnigsqd
mndnvwltlakkintdcdktdgfvithgtttmeetayfldltvkcdkpvvmvgamrpsts
msadgpfnlynavvtaadkasanrgvlvvmndtvldgrdvtttnttdvatfksvnygplg
yihngkidyqrtparkhtsdtpfdvsklnelpkvgivynyanasdlpakalvdagydgiv
sagvgngnlyksvfdtlataaktgtavvrssrvptgattqdaevddakygfvasgtlnpq
karvllqlaltqtkdpqqiqqifnqy

Sequence, based on observed residues (ATOM records):

>d6nx8b_ c.88.1.1 (B:) Asparaginase type II {Escherichia coli [TaxId: 562]}
lpnitilatggtiaggvenlvnavpqlkdianvkgeqvvnigsqdmndnvwltlakkint
dcdktdgfvithgtttmeetayfldltvkcdkpvvmvgamrpstsmsadgpfnlynavvt
aadkasanrgvlvvmndtvldgrdvtttnttdvatfksvnygplgyihngkidyqrtpar
khtsdtpfdvsklnelpkvgivynyanasdlpakalvdagydgivsagvgngnlyksvfd
tlataaktgtavvrssrvptgattqdaevddakygfvasgtlnpqkarvllqlaltqtkd
pqqiqqifnqy

Timeline for d6nx8b_:

• d6nx8b_ first appeared in SCOPe 2.07