Lineage for d6dtwa1 (6dtw A:1-429)

  1. Root: SCOPe 2.07
  2. 2568173Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)
  3. 2571153Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 2571154Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 2571504Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)
  6. 2571505Protein HIV-1 reverse transcriptase [56689] (4 species)
  7. 2571549Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (204 PDB entries)
    Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595
  8. 3072151Domain d6dtwa1: 6dtw A:1-429 [372212]
    Other proteins in same PDB: d6dtwa2, d6dtwa3
    automated match to d2be2a1
    complexed with h9y, mg, so4; mutant

Details for d6dtwa1

PDB Entry: 6dtw (more details), 2.74 Å

PDB Description: hiv-1 reverse transcriptase y181c mutant in complex with jlj 578
PDB Compounds: (A:) Reverse transcriptase/ribonuclease H

SCOPe Domain Sequences for d6dtwa1:

Sequence, based on SEQRES records: (download)

>d6dtwa1 e.8.1.2 (A:1-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfaaqnpdivi
cqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyql

Sequence, based on observed residues (ATOM records): (download)

>d6dtwa1 e.8.1.2 (A:1-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
fairklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkyt
aftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfaaqnpdivicqymddly
vgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpe
kdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenre
ilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkql
teavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
l

SCOPe Domain Coordinates for d6dtwa1:

Click to download the PDB-style file with coordinates for d6dtwa1.
(The format of our PDB-style files is described here.)

Timeline for d6dtwa1:

  • d6dtwa1 is new in SCOPe 2.07-stable

View in 3D
Domains from other chains:
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d6dtwb_