SCOPe 2.07: Domain d6qa4a_: 6qa4 A:

Lineage for d6qa4a_ (6qa4 A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein MAP kinase Erk2 [56134] (2 species)
   CMGC group; ERK/MAPK subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56135] (69 PDB entries)

8. Domain d6qa4a_: 6qa4 A: [371350]
   automated match to d1erka_
   complexed with hrz, so4

Details for d6qa4a_

PDB Entry: 6qa4, 1.6 Å

PDB Description: erk2 mini-fragment binding

PDB Compounds: (A:) Mitogen-activated protein kinase 1

SCOPe Domain Sequences for d6qa4a_:

Sequence, based on SEQRES records:

>d6qa4a_ d.144.1.7 (A:) MAP kinase Erk2 {Human (Homo sapiens) [TaxId: 9606]}
pemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrtlr
eikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyfl
yqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvat
rwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqe
dlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalah
pyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpg

Sequence, based on observed residues (ATOM records):

>d6qa4a_ d.144.1.7 (A:) MAP kinase Erk2 {Human (Homo sapiens) [TaxId: 9606]}
pemvrgqvfdvgprytnlsyigeggmvcsaydnvnkvrvaikkispfehqtycqrtlrei
killrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyflyq
ilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvatrw
yrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedl
nciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpy
leqyydpsdepiaeapfkpkeklkelifeetarfqpg

Timeline for d6qa4a_:

• d6qa4a_ is new in SCOPe 2.07-stable
  
• d6qa4a_ appears in the current release, SCOPe 2.08