SCOPe 2.08: Domain d6p69a_: 6p69 A:

Lineage for d6p69a_ (6p69 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Fibroblast growth factor receptor 1 [56158] (1 species)
   PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56159] (47 PDB entries)

8. Domain d6p69a_: 6p69 A: [371270]
   automated match to d4v04b_
   complexed with edo, o21, so4

Details for d6p69a_

PDB Entry: 6p69, 2.2 Å

PDB Description: crystal structure of fgfr1-y563c (fgfr4 surrogate) covalently bound to compound 11.

PDB Compounds: (A:) fibroblast growth factor receptor 1

SCOPe Domain Sequences for d6p69a_:

Sequence, based on SEQRES records:

>d6p69a_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
eyelpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdat
ekdlsdlisememmkmigkhkniinllgactqdgplyvivecaskgnlreylqarrppgl
eysynpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiad
fglardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspy
pgvpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivalt
snqe

Sequence, based on observed residues (ATOM records):

>d6p69a_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
eyelpedprwelprdrlvlgkplgegafgqvvlaeaiglpnrvtkvavkmlksdatekdl
sdlisememmkmigkhkniinllgactqdgplyvivecaskgnlreylqarrppeeqlss
kdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfglardihhidyykkt
tngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypgvpveelfkllkegh
rmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivaltsnqe

Timeline for d6p69a_:

• d6p69a_ first appeared in SCOPe 2.07