SCOPe 2.05: Domain d1deub_: 1deu B:

Lineage for d1deub_ (1deu B:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (23 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (26 proteins)

6. Protein (Pro)cathepsin X [54031] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [54032] (2 PDB entries)

8. Domain d1deub_: 1deu B: [37086]
   contains propeptide

Details for d1deub_

PDB Entry: 1deu, 1.7 Å

PDB Description: crystal structure of human procathepsin x: a cysteine protease with the proregion covalently linked to the active site cysteine

PDB Compounds: (B:) procathepsin x

SCOPe Domain Sequences for d1deub_:

Sequence, based on SEQRES records:

>d1deub_ d.3.1.1 (B:) (Pro)cathepsin X {Human (Homo sapiens) [TaxId: 9606]}
frrgqtcyrplrgdglaplgrttyprpheylspadlpkswdwrnvdgvnyasitrnqhip
qycgscwahastsamadrinikrkgawpstllsvqnvidcgnagsceggndlsvwdyahq
hgipdetcnnyqakdqecdkfnqcgtcnefkechairnytlwrvgdygslsgrekmmaei
yangpiscgimaterlanytggiyaeyqdttyinhvvsvagwgisdgteywivrnswgep
wgergwlrivtstykdgkgarynlaieehctfgdpiv

Sequence, based on observed residues (ATOM records):

>d1deub_ d.3.1.1 (B:) (Pro)cathepsin X {Human (Homo sapiens) [TaxId: 9606]}
frrgqtcyrplreylspadlpkswdwrnvdgvnyasitrnqhipqycgscwahastsama
drinikrkgawpstllsvqnvidcgnagsceggndlsvwdyahqhgipdetcnnyqakdq
ecdkfnqcgtcnefkechairnytlwrvgdygslsgrekmmaeiyangpiscgimaterl
anytggiyaeyqdttyinhvvsvagwgisdgteywivrnswgepwgergwlrivtstykd
gkgarynlaieehctfgdpiv

Timeline for d1deub_:

• d1deub_ first appeared (with stable ids) in SCOP 1.55
  
• d1deub_ appears in SCOPe 2.04
  
• d1deub_ appears in SCOPe 2.06
  
• d1deub_ appears in the current release, SCOPe 2.08