Lineage for d7pckc_ (7pck C:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2154577Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 2154578Superfamily d.3.1: Cysteine proteinases [54001] (24 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 2154579Family d.3.1.1: Papain-like [54002] (26 protein domains)
  6. 2154605Protein (Pro)cathepsin K [54028] (3 species)
  7. 2154606Species Human (Homo sapiens) [TaxId:9606] [54029] (51 PDB entries)
    Uniprot P43235 116-329 ! Uniprot P43235 115-329
  8. 2154656Domain d7pckc_: 7pck C: [37081]
    contains propeptide

Details for d7pckc_

PDB Entry: 7pck (more details), 3.2 Å

PDB Description: crystal structure of wild type human procathepsin k
PDB Compounds: (C:) protein (procathepsin k)

SCOPe Domain Sequences for d7pckc_:

Sequence, based on SEQRES records: (download)

>d7pckc_ d.3.1.1 (C:) (Pro)cathepsin K {Human (Homo sapiens) [TaxId: 9606]}
lypeeildthwelwkkthrkqynnkvdeisrrliweknlkyisihnleaslgvhtyelam
nhlgdmtseevvqkmtglkvplshsrsndtlyipewegrapdsvdyrkkgyvtpvknqgq
cgscwafssvgalegqlkkktgkllnlspqnlvdcvsendgcgggymtnafqyvqknrgi
dsedaypyvgqeescmynptgkaakcrgyreipegnekalkravarvgpvsvaidaslts
fqfyskgvyydescnsdnlnhavlavgygiqkgnkhwiiknswgenwgnkgyilmarnkn
nacgianlasfpkm

Sequence, based on observed residues (ATOM records): (download)

>d7pckc_ d.3.1.1 (C:) (Pro)cathepsin K {Human (Homo sapiens) [TaxId: 9606]}
lypeeildthwelwkkthrkqynnkvdeisrrliweknlkyisihnleaslgvhtyelam
nhlgdmtseevvqkmtglkvplndtlyipewegrapdsvdyrkkgyvtpvknqgqcgscw
afssvgalegqlkkktgkllnlspqnlvdcvsendgcgggymtnafqyvqknrgidseda
ypyvgqeescmynptgkaakcrgyreipegnekalkravarvgpvsvaidasltsfqfys
kgvyydescnsdnlnhavlavgygiqkgnkhwiiknswgenwgnkgyilmarnknnacgi
anlasfpkm

SCOPe Domain Coordinates for d7pckc_:

Click to download the PDB-style file with coordinates for d7pckc_.
(The format of our PDB-style files is described here.)

Timeline for d7pckc_: