SCOP 1.71: Domain d1cjl__: 1cjl -

Lineage for d1cjl__ (1cjl -)

1. Root: SCOP 1.71

2. Class d: Alpha and beta proteins (a+b) [53931] (286 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (12 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (23 proteins)

6. Protein (Pro)cathepsin L [54026] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [54027] (4 PDB entries)

8. Domain d1cjl__: 1cjl - [37066]
   contains propeptide
   mutant

Details for d1cjl__

PDB Entry: 1cjl, 2.2 Å

PDB Description: crystal structure of a cysteine protease proform

SCOP Domain Sequences for d1cjl__:

Sequence, based on SEQRES records:

>d1cjl__ d.3.1.1 (-) (Pro)cathepsin L {Human (Homo sapiens)}
dhsleaqwtkwkamhnrlygmneegwrravweknmkmielhnqeyregkhsftmamnafg
dmtseefrqvmnglqnrkprkgkvfqeplfyeaprsvdwrekgyvtpvknqgqcgsswaf
satgalegqmfrktgrlislseqnlvdcsgpegnegcngglmdyafqyvqdnggldsees
ypyeateesckynpkysvandagfvdipkqekalmkavatvgpisvaidaghesflfyke
giyfepdcssedmdhgvlvvgygfestesdgnkywlvknswgeewgmggyvkmakdrrnh
cgiasaasyptv

Sequence, based on observed residues (ATOM records):

>d1cjl__ d.3.1.1 (-) (Pro)cathepsin L {Human (Homo sapiens)}
dhsleaqwtkwkamhnrlygmneegwrravweknmkmielhnqeyregkhsftmamnafg
dmtseefrqvmnglqnrkprkgkvfqeplfyeaprsvdwrekgyvtpvknqgqcgsswaf
satgalegqmfrktgrlislseqnlvdcsgpegnegcngglmdyafqyvqdnggldsees
ypyeateesckynpkysvandagfvdipkqekalmkavatvgpisvaidaghesflfyke
giyfepdcssedmdhgvlvvgygfesnkywlvknswgeewgmggyvkmakdrrnhcgias
aasyptv

Timeline for d1cjl__:

• d1cjl__ first appeared (with stable ids) in SCOP 1.55
  
• d1cjl__ appears in SCOP 1.69
  
• d1cjl__ is called d1cjla_ in SCOP 1.73
  
• d1cjl__ appears in the current release, SCOPe 2.08, called d1cjla_