SCOPe 2.08: Domain d1cjla_: 1cjl A:

Lineage for d1cjla_ (1cjl A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (26 proteins)

6. Protein (Pro)cathepsin L [54026] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [54027] (4 PDB entries)

8. Domain d1cjla_: 1cjl A: [37066]
   contains propeptide
   has additional insertions and/or extensions that are not grouped together

Details for d1cjla_

PDB Entry: 1cjl, 2.2 Å

PDB Description: crystal structure of a cysteine protease proform

PDB Compounds: (A:) procathepsin l

SCOPe Domain Sequences for d1cjla_:

Sequence, based on SEQRES records:

>d1cjla_ d.3.1.1 (A:) (Pro)cathepsin L {Human (Homo sapiens) [TaxId: 9606]}
dhsleaqwtkwkamhnrlygmneegwrravweknmkmielhnqeyregkhsftmamnafg
dmtseefrqvmnglqnrkprkgkvfqeplfyeaprsvdwrekgyvtpvknqgqcgsswaf
satgalegqmfrktgrlislseqnlvdcsgpegnegcngglmdyafqyvqdnggldsees
ypyeateesckynpkysvandagfvdipkqekalmkavatvgpisvaidaghesflfyke
giyfepdcssedmdhgvlvvgygfestesdgnkywlvknswgeewgmggyvkmakdrrnh
cgiasaasyptv

Sequence, based on observed residues (ATOM records):

>d1cjla_ d.3.1.1 (A:) (Pro)cathepsin L {Human (Homo sapiens) [TaxId: 9606]}
dhsleaqwtkwkamhnrlygmneegwrravweknmkmielhnqeyregkhsftmamnafg
dmtseefrqvmnglqnrkprkgkvfqeplfyeaprsvdwrekgyvtpvknqgqcgsswaf
satgalegqmfrktgrlislseqnlvdcsgpegnegcngglmdyafqyvqdnggldsees
ypyeateesckynpkysvandagfvdipkqekalmkavatvgpisvaidaghesflfyke
giyfepdcssedmdhgvlvvgygfesnkywlvknswgeewgmggyvkmakdrrnhcgias
aasyptv

Timeline for d1cjla_:

• d1cjla_ first appeared (with stable ids) in SCOP 1.55, called d1cjl__
  
• d1cjla_ appears in SCOPe 2.07