SCOPe 2.07: Domain d6k9ua_: 6k9u A:

Lineage for d6k9ua_ (6k9u A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (10 species)
   not a true protein

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [255521] (12 PDB entries)

8. Domain d6k9ua_: 6k9u A: [370574]
   automated match to d5axqb_
   complexed with d4l, mg, so4, zn

Details for d6k9ua_

PDB Entry: 6k9u, 2.35 Å

PDB Description: discovery of pyrazolo[1,5-a]pyrimidine derivative as a highly selective pde10a inhibitor

PDB Compounds: (A:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d6k9ua_:

Sequence, based on SEQRES records:

>d6k9ua_ a.211.1.0 (A:) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}
lparicrdielfhfdigpfenmwpgifvymihrscgtscfeleklcrfimsvkknyrrvp
yhnwkhavtvahcmyailqnnnglftdlerkglliaclchdldhrgfsnsylqkfdhpla
alyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlalyfgnrk
qleemyqtgslnlhnqshrdrviglmmtacdlcsvtklwpvtkltandiyaefwaegdem
kklgiqpipmmdrdkrdevpqgqlgfynavaipcyttltqilpptepllkacrdnlnqwe
kvirgee

Sequence, based on observed residues (ATOM records):

>d6k9ua_ a.211.1.0 (A:) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}
lparicrdielfhfdigpfenmwpgifvymihrsfeleklcrfimsvkknyrrvpyhnwk
havtvahcmyailqnnnglftdlerkglliaclchdldhrgfsnsylqkfdhplaalyst
stmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlalyfgnrkqleem
yqtgslnlhnqshrdrviglmmtacdlcsvtklwpvtkltandiyaefwaegdemkklgi
qpipmmdrdkrdevpqgqlgfynavaipcyttltqilpptepllkacrdnlnqwekvirg
ee

Timeline for d6k9ua_:

• d6k9ua_ is new in SCOPe 2.07-stable
  
• d6k9ua_ appears in the current release, SCOPe 2.08