SCOPe 2.08: Domain d6jcoa4: 6jco A:384-532

Lineage for d6jcoa4 (6jco A:384-532)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.109: Gelsolin-like [55752] (3 superfamilies)
   3 layers: a/b/a; contains mixed beta-sheet

4. Superfamily d.109.1: Actin depolymerizing proteins [55753] (3 families)

5. Family d.109.1.1: Gelsolin-like [55754] (5 proteins)

6. Protein Gelsolin [55759] (2 species)
   consists of six similar domains

7. Species Human (Homo sapiens) [TaxId:9606] [55761] (47 PDB entries)
   Uniprot P20065 55-179

8. Domain d6jcoa4: 6jco A:384-532 [370492]
   automated match to d1d0na4
   mutant

Details for d6jcoa4

PDB Entry: 6jco, 2.88 Å

PDB Description: crystal structure of calcium free human gelsolin amyloid mutant d187n

PDB Compounds: (A:) gelsolin

SCOPe Domain Sequences for d6jcoa4:

Sequence, based on SEQRES records:

>d6jcoa4 d.109.1.1 (A:384-532) Gelsolin {Human (Homo sapiens) [TaxId: 9606]}
sshianvervpfdaatlhtstamaaqhgmdddgtgqkqiwriegsnkvpvdpatygqfyg
gdsyiilynyrhggrqgqiiynwqgaqstqdevaasailtaqldeelggtpvqsrvvqgk
epahlmslfggkpmiiykggtsreggqta

Sequence, based on observed residues (ATOM records):

>d6jcoa4 d.109.1.1 (A:384-532) Gelsolin {Human (Homo sapiens) [TaxId: 9606]}
sshianvervpfdaatlhtstamaaqhgmdddgtgqkqiwriegsnkvpvdpatygqfyg
gdsyiilynyrhggrqgqiiynwqgaqstqdevaasailtaqldeelggtpvqsrvvqgk
epahlmslfggkpmiiykggtsregqta

Timeline for d6jcoa4:

• d6jcoa4 first appeared in SCOPe 2.07