SCOPe 2.06: Domain d1f29a_: 1f29 A:

Lineage for d1f29a_ (1f29 A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (26 proteins)

6. Protein Cruzain [54020] (1 species)

7. Species Trypanosoma cruzi [TaxId:5693] [54021] (25 PDB entries)

8. Domain d1f29a_: 1f29 A: [37045]
   complexed with vs1

Details for d1f29a_

PDB Entry: 1f29, 2.15 Å

PDB Description: crystal structure analysis of cruzain bound to a vinyl sulfone derived inhibitor (i)

PDB Compounds: (A:) cruzain

SCOPe Domain Sequences for d1f29a_:

Sequence; same for both SEQRES and ATOM records:

>d1f29a_ d.3.1.1 (A:) Cruzain {Trypanosoma cruzi [TaxId: 5693]}
apaavdwrargavtavkdqgqcgscwafsaignvecqwflaghpltnlseqmlvscdktd
sgcsgglmnnafewivqenngavytedsypyasgegisppcttsghtvgatitghvelpq
deaqiaawlavngpvavavdasswmtytggvmtscvseqldhgvllvgyndsaavpywii
knswttqwgeegyiriakgsnqclvkeeassavvg

Timeline for d1f29a_:

• d1f29a_ first appeared (with stable ids) in SCOP 1.55
  
• d1f29a_ appears in SCOPe 2.05
  
• d1f29a_ appears in SCOPe 2.07
  
• d1f29a_ appears in the current release, SCOPe 2.08