Lineage for d6h4pb_ (6h4p B:)

  1. Root: SCOPe 2.08
  2. Class b: All beta proteins [48724] (180 folds)
  3. Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. Family b.82.2.14: Jumonji domain / Histone demethylase core [254153] (7 proteins)
    Jumonji domain; Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801
    Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801; some members include C-terminal helical subdomain (Pfam PF17811)
  6. Protein JMJD2A core [254342] (1 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [254775] (57 PDB entries)
  8. Domain d6h4pb_: 6h4p B: [370137]
    automated match to d5f2sb_
    complexed with cl, dms, fq5, gol, zn

Details for d6h4pb_

PDB Entry: 6h4p (more details), 2.19 Å

PDB Description: crystal structure of human kdm4a in complex with compound 16a
PDB Compounds: (B:) lysine-specific demethylase 4a

SCOPe Domain Sequences for d6h4pb_:

Sequence, based on SEQRES records: (download)

>d6h4pb_ b.82.2.14 (B:) JMJD2A core {Human (Homo sapiens) [TaxId: 9606]}
esetlnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddid
dlvipapiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywk
nltfnppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwkt
sfawhtedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmt
lisplmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqa
vlcscrkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaef

Sequence, based on observed residues (ATOM records): (download)

>d6h4pb_ b.82.2.14 (B:) JMJD2A core {Human (Homo sapiens) [TaxId: 9606]}
esetlnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddid
dlvipapiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywk
nltfnppiygadvngtlyekhvdewnigrlrtildlvegvntpylyfgmwktsfawhted
mdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlisplmlk
kygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlcscrkm
vkismdvfvrkfqperyklwkagkdntvidhtlptpeaaef

SCOPe Domain Coordinates for d6h4pb_ are not available.

Timeline for d6h4pb_:

View in 3D
Domains from other chains:
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d6h4pa_, d6h4pc_, d6h4pd_