Lineage for d6h4tc_ (6h4t C:)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2403751Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. 2404605Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. 2404954Family b.82.2.14: Histone demethylase core [254153] (4 proteins)
    Jumonji domain; Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801
  6. 2404958Protein JMJD2A core [254342] (1 species)
  7. 2404959Species Human (Homo sapiens) [TaxId:9606] [254775] (57 PDB entries)
  8. 3070071Domain d6h4tc_: 6h4t C: [370133]
    automated match to d5f2sb_
    complexed with cl, dms, fow, gol, zn

Details for d6h4tc_

PDB Entry: 6h4t (more details), 2.38 Å

PDB Description: crystal structure of human kdm4a in complex with compound 19a
PDB Compounds: (C:) lysine-specific demethylase 4a

SCOPe Domain Sequences for d6h4tc_:

Sequence, based on SEQRES records: (download)

>d6h4tc_ b.82.2.14 (C:) JMJD2A core {Human (Homo sapiens) [TaxId: 9606]}
psarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddlvipa
piqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknltfnp
piygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwktsfawht
edmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlisplm
lkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlcscr
kdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaefl

Sequence, based on observed residues (ATOM records): (download)

>d6h4tc_ b.82.2.14 (C:) JMJD2A core {Human (Homo sapiens) [TaxId: 9606]}
psarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddlvipa
piqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknltfnp
piygadvngtlyekhvdewnigrlrtildlvekesegvntpylyfgmwktsfawhtedmd
lysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlisplmlkky
gipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlcscrvkis
mdvfvrkfqperyklwkagkdntvidhtlptpeaaefl

SCOPe Domain Coordinates for d6h4tc_:

Click to download the PDB-style file with coordinates for d6h4tc_.
(The format of our PDB-style files is described here.)

Timeline for d6h4tc_:

  • d6h4tc_ is new in SCOPe 2.07-stable