SCOPe 2.08: Domain d6gx0a1: 6gx0 A:64-345

Lineage for d6gx0a1 (6gx0 A:64-345)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.68: Nucleotide-diphospho-sugar transferases [53447] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3214657; strand 6 is antiparallel to the rest

4. Superfamily c.68.1: Nucleotide-diphospho-sugar transferases [53448] (20 families)

5. Family c.68.1.9: alpha-1,3-galactosyltransferase-like [64131] (4 proteins)
   automatically mapped to Pfam PF03414

6. Protein Glycosyltransferase A catalytic domain [75276] (1 species)
   involved in blood group antigen biosynthesis

7. Species Human (Homo sapiens) [TaxId:9606] [75277] (59 PDB entries)
   Uniprot P16442 64-345

8. Domain d6gx0a1: 6gx0 A:64-345 [370068]
   Other proteins in same PDB: d6gx0a2
   automated match to d1lzia_
   complexed with edo, gdu, mn, peg, so4

Details for d6gx0a1

PDB Entry: 6gx0, 1.25 Å

PDB Description: blood group synthase aaglyb in complex with udp-gal and cryoprotected with peg 3350

PDB Compounds: (A:) ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase)

SCOPe Domain Sequences for d6gx0a1:

Sequence; same for both SEQRES and ATOM records:

>d6gx0a1 c.68.1.9 (A:64-345) Glycosyltransferase A catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
vslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttigltvfai
kkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevraykrwqd
vsmrrmemisdfcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpgfygssrea
ftyerrpqsqayipkdegdfyyggaffggsvqevqrltrachqammvdqangieavwhde
shlnkyllrhkptkvlspeylwdqqllgwpavlrklrftavp

Timeline for d6gx0a1:

• d6gx0a1 first appeared in SCOPe 2.07