SCOPe 2.07: Domain d6h14b_: 6h14 B:

Lineage for d6h14b_ (6h14 B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein automated matches [190065] (7 species)
   not a true protein

7. Species Tetronarce californica [TaxId:7787] [350659] (10 PDB entries)

8. Domain d6h14b_: 6h14 B: [368828]
   automated match to d2xugb_
   complexed with cl, edo, fw8, gol, mes, nag, peg, pge, so4

Details for d6h14b_

PDB Entry: 6h14, 1.86 Å

PDB Description: crystal structure of tcache complexed to 1-(6-oxo-1,2,3,4,6,10b- hexahydropyrido[2,1-a]isoindol-10-yl)-3-(4-(1-(2-((1,2,3,4- tetrahydroacridin-9-yl)amino)ethyl)-1h-1,2,3-triazol-4-yl)pyridin-2- yl)urea

PDB Compounds: (B:) acetylcholinesterase

SCOPe Domain Sequences for d6h14b_:

Sequence, based on SEQRES records:

>d6h14b_ c.69.1.1 (B:) automated matches {Tetronarce californica [TaxId: 7787]}
sellvntksgkvmgtrvpvlsshisaflgipfaeppvgnmrfrrpepkkpwsgvwnasty
pnncqqyvdeqfpgfsgsemwnpnremsedclylniwvpsprpksttvmvwiygggfysg
sstldvyngkylayteevvlvslsyrvgafgflalhgsqeapgnvglldqrmalqwvhdn
iqffggdpktvtifgesaggasvgmhilspgsrdlfrrailqsgspncpwasvsvaegrr
ravelgrnlncnlnsdeelihclrekkpqelidvewnvlpfdsifrfsfvpvidgeffpt
slesmlnsgnfkktqillgvnkdegsffllygapgfskdseskisredfmsgvklsvpha
ndlgldavtlqytdwmddnngiknrdglddivgdhnvicplmhfvnkytkfgngtylyff
nhrasnlvwpewmgvihgyeiefvfglplvkelnytaeeealsrrimhywatfaktgnpn
ephsqeskwplfttkeqkfidlntepmkvhqrlrvqmcvfwnqflpkllnat

Sequence, based on observed residues (ATOM records):

>d6h14b_ c.69.1.1 (B:) automated matches {Tetronarce californica [TaxId: 7787]}
sellvntksgkvmgtrvpvlsshisaflgipfaeppvgnmrfrrpepkkpwsgvwnasty
pnncqqyvdeqfpgfsgsemwnpnremsedclylniwvpsprpksttvmvwiygggfysg
sstldvyngkylayteevvlvslsyrvgafgflalhgsqeapgnvglldqrmalqwvhdn
iqffggdpktvtifgesaggasvgmhilspgsrdlfrrailqsgspncpwasvsvaegrr
ravelgrnlncnlnsdeelihclrekkpqelidvewnvlpfdsifrfsfvpvidgeffpt
slesmlnsgnfkktqillgvnkdegsffllygapgfskdseskisredfmsgvklsvpha
ndlgldavtlqytdwmddnngiknrdglddivgdhnvicplmhfvnkytkfgngtylyff
nhrasnlvwpewmgvihgyeiefvfglplvkelnytaeeealsrrimhywatfaktgnpn
ephsskwplfttkeqkfidlntepmkvhqrlrvqmcvfwnqflpkllnat

Timeline for d6h14b_:

• d6h14b_ is new in SCOPe 2.07-stable
  
• d6h14b_ appears in the current release, SCOPe 2.08