SCOPe 2.08: Domain d6njhd_: 6njh D:

Lineage for d6njhd_ (6njh D:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (9 families)

5. Family a.211.1.2: PDEase [48548] (7 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein Catalytic domain of cyclic nucleotide phosphodiesterase pde4d [89151] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89152] (89 PDB entries)
   Uniprot Q08499 388-713

8. Domain d6njhd_: 6njh D: [368629]
   automated match to d3iada_
   complexed with krd, mg, zn

Details for d6njhd_

PDB Entry: 6njh, 2.15 Å

PDB Description: crystal structure of the pde4d catalytic domain and ucr2 regulatory helix with t-48

PDB Compounds: (D:) cAMP-specific 3',5'-cyclic phosphodiesterase 4D

SCOPe Domain Sequences for d6njhd_:

Sequence, based on SEQRES records:

>d6njhd_ a.211.1.2 (D:) Catalytic domain of cyclic nucleotide phosphodiesterase pde4d {Human (Homo sapiens) [TaxId: 9606]}
edvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipvdtlitylmt
ledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasaihdvdhpgvs
nqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqslrkmvidiv
latdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcadlsnptkplql
yrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhplwetwadlv
hpdaqdildtlednrewyqstipqapappldeqnrdsqgnqvsefisntfld

Sequence, based on observed residues (ATOM records):

>d6njhd_ a.211.1.2 (D:) Catalytic domain of cyclic nucleotide phosphodiesterase pde4d {Human (Homo sapiens) [TaxId: 9606]}
edvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipvdtlitylmt
ledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasaihdvdhpgvs
nqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqslrkmvidiv
latdmskhmnlladlktmvetkkvtvllldnysdriqvlqnmvhcadlsnptkplqlyrq
wtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhplwetwadlvhpd
aqdildtlednrewyqstipnqvsefisntfld

Timeline for d6njhd_:

• d6njhd_ first appeared in SCOPe 2.07